Improving Black Health Outcomes

• This initiative aims to advance research on health conditions that disproportionately affect Black communities, including Sickle Cell Disease, Thalassemia, diabetes, and cardiovascular diseases.
• They are looking for participants in Leeds with Sickle Cell Disease or Thalassemia to take part in this vital study. While the research focuses on Black communities, they also welcome participants from Asian and other ethnic backgrounds, as further research is crucial to improving understanding of these conditions and developing better treatments.
• The below leaflet includes further details, including how potential participants can contact the Leeds Research team. There is also an incentive for taking part.
• The below leaflet includes further details, including how potential participants can contact the Leeds Research team. There is also an incentive for taking part.

Information about a clinical study for a new device for diabetes

• Eligible patients will be contacted by the study team.
• We would like to speak to you to discuss a clinical study for a new device for diabetes.
• The study is assessing a new sensor for monitoring of your sugar levels.
• We are looking for people who:
  • Have Type 2 diabetes
  • Use long-acting, background insulin once or twice a day
  • Take other medications to lower blood sugar belonging to;
  • SGLT2 inhibitor class (drugs like Empagliflozin, Dapagliflozin or Cangliflozin)
  • GLP-1 (drugs like Semaglutide, Dulaglutide)
  • Are willing to wear the FreeStyle Libre 3 glucose sensor as part of a research study

• We believe you may be suitable for this study and would like to discuss it in more detail with you.
  Below is a summary of the study:
• The study will last for up to 12 months and during this time you will have reviews with a diabetes specialist to look at your diabetes management.
• At the start of the study, you will wear a sensor on your arm for approximately 14 days. Then you will be randomly allocated to either continue using your current glucose monitoring method or you will be asked to wear a FreeStyle Libre 3 for 8 months.
• During the study, you will also be asked to:
  • Give blood samples for diabetes related laboratory tests at the start, middle and the end of the study.
  • Have in-person or virtual reviews with a diabetes specialist.
  • Complete questionnaires about your diabetes experience.

• Any allocated to continue with their current glucose monitoring method will be offered an optional 4- month period of FreeStyle Libre 3 use after 8 months.
• Participation in this study is entirely your choice and you are free to decide not to take part or to withdraw from the study at any time without having to give a reason. This will have no effect on your future medical treatment.
• You will be reimbursed for time and any reasonable travel costs associated with attending study visits.

Panthera

• We have been working closely with The North Leeds Medical Practice for patient recruitment in clinical research studies.
• Their collaboration has been instrumental in advancing clinical research, particularly in cardiovascular studies, where we have seen strong patient engagement. Their support in facilitating patient participation has been invaluable, making them a trusted and essential partner in our mission to improve healthcare through clinical research.
• We look forward to continuing this successful partnership and furthering our shared commitment to medical advancement in the years to come.

ECAL Trial

ASR – Aging and Stroke Research

The INCLUDE study: Development of methods to identify digitally excluded older people, and tailoring of interventions to meet their digital needs

• We are currently interviewing a range of older people about their digital use and experiences of being online, or not. We are also reviewing the published literature to see what types of digital support appear to be effective.  We have talked to providers of digital support services across the region about how they support older people to get online.
• For more information on the study, please visit their website: https://ageingstrokeresearch.org/research-projects/include/.